Background/Aims:
@EN The aim of this study was to evaluate acid clearance in esophageal disease, a common cause of noncardiac chest pain, and to evaluate the correlation between the swallowing number for acid clearance and the amplitude of contractions.
@ES Methods:
@EN The study population was divided into four groups., Group I (n=8) was controls with no complaints of any gastrointestinal symptoms. Group II (n=9) was gastroesophageal reflux disease. Group III (n=6) was nutcracker esophagus. Group IV(n=7)
was
nonspecific esophageal motility disorder with low amplitude contractions. We performed standard acid clearance test and compared it with the amplitude of esophageal contractions.
@ES Results:
@EN In Group I, the swallowing number was 6.12±0.58 (mean±SE); in Group II, 15.33±3.96; and in Group III and IV, 9.83±2.70 and 20.42±4.43 respectively. The number of swallowing was significantly increased in Group IV than in the other groups
(P<0.05) and showed the reversed correlation with amplitude (r=-0.81, p=0.026).
@ES Conclusions:
@EN Group IV had significantly delayed esophageal acid clearance and also showed the reversed correlation with amplitude. (Korean J Gastroenterol 1995; 27: 493-498)
|